The Buff/Debuff Icon system will allow players to quickly and easily identify effects applied to their character. In addition to displaying an icon for the effects listed below, mousing over an icon will show a tooltip that displays additional information.
You can turn these off by making a macro that toggles the targeting reticle on and off, and the buff bar.
See the link below for a full list of icons
http://update.uo.com/design_523.html